Seizure susceptibility is altered by exposure to morphine during mid to late gestation period in the rat

Abstract

This book chapter summarize the long-term effects of prenatal morphine exposure on adult male and female seizure susceptibility. We provide valuable insight into the mechanisms of how opioids can exert detrimental influences on the developing organism.

Keywords

• chemoconvulsants
• development
• GABA
• gonadal hormones
• kainic acid
• morphine
• NMDA
• opioids
• prenatal exposure
• seizures
• sex differences
• rat