Chronic mild inflammation links obesity, metabolic syndrome, atherosclerosis and diabetes

Abstract

Chronic low grade inflammation is a relatively new concept in metabolic medicine. This concept describes the relations between the inflammation and adipose tissue, insulin resistance, atherosclerosis and type 2 diabetes mellitus.

Macrophages and lymphocytes deposed in adipose tissue produce proinflammatory cytokines wich directly or through the CRP liver secretion target endothelias cells, hepatocytes and pancreatic ß-cells.

Keywords

• chronic low grade inflammation
• metabolic syndrome
• type 2 diabetes mellitus
• cytokines