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Aspirin resistance after coronary artery bypass grafting

Publication at Third Faculty of Medicine |
2010

Abstract

Aspirin administration after surgical myocardial revascularization improves not only early patency, particularly that of the venous grafts but, also, and more importantly, it significantly improves clinical postoperative outcomes. Several recent papers have consistently reported an inadequate inhibitory effect of aspirin on platelet function in the early postoperative period, giving rise to what is now referred to as acquired aspirin insuffi ciency (resistance).

The paper is an extensive overview of current concepts regarding the issue including its pathogenesis, diagnosis, and clinical relevance. The paper includes a list of the authors' own publications addressing the topic