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Relapse frequency and quality of life in day-treatment programme for psychotic disorders: one-year outcomes

Publication at Central Library of Charles University |
2010

Abstract

Day-treatment programme represents an optimal environment for psychiatric rehabilitation of patiens with schizophrenia spectrum disorders. We introduce clinically-based 6-week structured group day-treatment programme for out-patients with schizophrenia-spectrum disorders in the stabilization phase of the treatment.

To assess relapse frequency, psychopathology (PANSS) and quality of life (Schwartz Outcomes Scale-10, SOS-10; WHO-QOL-BREF and Social Integration Survey, SIS) we designed one-year prospective follow-up field study. After informed consent procedure 144 patients entered the project (males N=77) between June 2005 and September 2008.

One-year relapse rate in participants (N=105) was 11%. Psychopatology decreased after programme significantly (p <.001) and PANSS scores remained low in one-year follow-up.

Quality of life assessed by SOS-10 improved after programme significantly (p=.016) and non-significantly continued to improve after one-year follow-up (p =.094). After the programme WHOQOL-BREF scores raised significantly in Subjective health domain (p =.001) and Psychological health (p = .009).

In one-year follow-up Environment domain improved significantly (p =.048). Social quality of life (SIS) improved in Behaviour to strangers (p = .028), Communication (p=.004), Activities of daily living (p=.019) and Empathy (p=.006).

Quality of life in patiens was lower compared to common population, improved after the programme (week 6) and this improvement was stable in one-year follow-up