White matter hyperintensities in offspring of bipolar parents-results from Czech sample

Abstract

White matter hyperintensities (WMHs) are among the most replicated neuroimaging findings in bipolar disorder (BD). It is not clear whether these lesions are an artifacts of comorbid conditions, directly associated with the illness and even possibly represent biological marketrs for the illness

Keywords

• white matter hyperintensities
• MRI
• bipolar disorder
• endophenotypes