Embryotoxicity of Mirtazapine a study using Chick Embryotoxicity Screening Test

Abstrakt

Aim of the study was to contribute to the knowledge on possible risk to the embryo after mirtazapine treatment. An alternative method (CHEST) was used for embryototicity testing.

LD 50 and embryotoxic dose was established. As both are close each other the risk for therapeutic dose is probably low.

Klíčová slova

• embryotoxicity
• screening test
• mirtazapine