Abstract
We summarized modern trends in treatment of severe spasticity that worsened quality of life, mobility and self-care of disabled patients. Spasticity is a result of lesion of pyramidal tract with loss of inhibitory influence of motor cortex on spinal motoneuron.
In mild spasticity combination of physical and pharmacological therapy and is recommended. A local administration of botulinum toxin into muscle is suitable for focal spasticity in a small muscle group.
In severe flexed spasticity of lower extremities, surgical ablation procedures may be performed. In severe generalized spasticity intrathecal continuous baclofen delivery is a method of very successful treatment.
Treatment of spasticity is a long-term process with multidisciplinary approach.