Synthesis of C-2-symmetrical [1,1 '-binaphthalene]-2,2 '-diamines with additional chelating groups attached to the nitrogen atoms as potential ligands for asymmetric catalysis

Abstract

Reductive amination of 2-hydroxybenzaldehyde, using a combination of NaBH4 and (R)-[1,1'-binaphthalene]-2,2'-diamine, served as the key step in the synthesis of the potentially tetradentate ligands.