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Carcinogenic and nephrotoxic alkaloids aristolochic acids upon activation by D,T-diaphorase from adducts found in DNA of patients with chinese herbs nephropathy

Publikace na 1. lékařská fakulta, Matematicko-fyzikální fakulta |
2001

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Aristolochic acid, a naturally occurring nephrotoxin and carcinogen, is implicated in a unique type of fibrosis, designated Chinese herbs nephropathy. This is the first report demonstrating an activation of aristolochic acid by D,T-diaphorase.