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Carcinogenic and nephrotoxic alkaloids aristolochic acids are activated by D,T-diaphorase: 32P-postlabeling analysis of DNA adduct formation

Publication at First Faculty of Medicine, Faculty of Mathematics and Physics |
2001
2 people

Abstract

D,T-diaphorase possesses nitroreductase activity for naturally occurring nephrotoxic and carcinogenic nitrofenathrene derivative, aristolochic acid.

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