Carcinogenic and nephrotoxic alkaloids aristolochic acids are activated by D,T-diaphorase: 32P-postlabeling analysis of DNA adduct formation

Publikace na 1. lékařská fakulta, Matematicko-fyzikální fakulta |

2001

D,T-diaphorase possesses nitroreductase activity for naturally occurring nephrotoxic and carcinogenic nitrofenathrene derivative, aristolochic acid.