Charles Explorer logo
🇨🇿

The interaction between the anticancer drug ellipticine and cytochromes P450 dictates its pharmacological efficiencies

Publikace na 1. lékařská fakulta, Matematicko-fyzikální fakulta |
2003

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

Five metabolites containining an oxygene atom in their molecules are generated from ellipticine by CYPs. Ellipticine inhibits microsomal CYP-dependent activities and interacts with CYPs exhibiting a reverse type binding spectrum.