Molecular Dynamics Study of the Effect of the γ-Abu Insert on the Conformational Behavior of the Glycopeptide Dendrimers Based on the Oligolysine Scaffold in N, N'-dimethylformamide

Abstrakt

Glycodendrimers bearing Tn (α-D-GalNAc-(1->O)-Ser/Thr) were characterized: a) distances of free, or extended termini from the anchor, b) interatomic distances between free or substituted N termini, c) radius of gyration and d) spatial distribution.