Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.

Publikace na 1. lékařská fakulta, Matematicko-fyzikální fakulta |

1999

Abstrakt

Aristolactam I is a detoxication metabolite of carcinogenic alkaloid aristolochic acid I. After activation of this metabolite by peroxidase and cytochrome P450 the DNA adduts are formed.

Aristolactam I a metabolite of aristolochic acid I upon activation forms an adduct found in DNA of patients with Chinese herbs nephropathy.

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

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