G Proteins,ß-Adrenoceptors and ß-Adrenergic Responsiveness Immature and Adult Rat Ventricular Myocardium:Influence of Neonatal Hypo- and Hyperthyroidism

Abstract

Physiological level of thyroid hormones is an important modulator of the normal maturation of the ß-adrenegic system in the developing rat ventricular myocardium. In adult rats previously affected by altered thyroid status,the function of their myocardiaß-adrenegic signaling appears to be compensated despite a lower number of the receptors.