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Ellipticine and Ellipticinium-human serum albumin (Elli-HSA) conjugate are cytotoxic and form covalent DNA adducts detected by 32P-postlabelling.

Publikace na 1. lékařská fakulta, Matematicko-fyzikální fakulta |
1999
6 osob

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

A new mechasnism of action of anticancer drug ellipticine and its conjugate with human serum albumin is described. This mechanism is a formation of covalent DNA adducts in vitro and in cells in culture.

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