Intravenous irradiation of blood using 337 nm laser in rabbits inoculated with Staphyloccoccus aureus
Abstract
Reinfusion of ultraviolet (UV) - irradiated blood with maximum absorption of 254 nm and 365 nm revealed the therapeutic effect on the course of staphylococcal infection. This method of irradiation is however less applicable in practical use because it strictly requires to keep the sterility, Thus we decided to study the therapeutic effect of UV blood irradiation in vivo using a laser connected with quartz-quartz optical fiber with maximum irradiation wavelength at 337 nm.
Our results show a good therapeutic effect of this method. All control rabbits inoculated with a virulent strain of Staphylococcus aureus H 476 died within 48 hours after infection.
In contrast, rabbits inoculated with the same size dose of Staphylococcus aureus but treated with in vivo UV-irradiated blood survived within 30 days of observation and no serious pathological changes were found in sections.