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HPLC analysis of amlodipine and plasma protein binding of its enantiomers

Publication at Faculty of Pharmacy in Hradec Králové |
2004

Abstract

Protein binding of amlodipine enantiomers in human and rat plasma was studied by equilibrium dialysis and achiral HPLC; binding of amlodipine to plasma proteins of both species was relatively high (92 %)