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Inactivation of the anticancer drugs doxorubicin and oracin by aldo-keto reductase (AKR) 1C3

Publication at Faculty of Pharmacy in Hradec Králové |
2008

Abstract

In the present study, we produced recombinant AKR1C3 and provided evidence that this AKR1C3 member catalyzes the inactivation of oracin and doxorubicin with high efficiency