Synthesis of 3,6-disubstituted pyranones analogous to antifungally active butenolides and unexpected loss of their biological effects

Abstract

A series of 3,6-disubstituted pyranones analogous to antifungally active butenolides was prepared, and their biological properties were evaluated

Keywords

• pyranones
• pentenolides
• biological activity
• synthesis
• Pd-catalysis