The use of Toppliss approach to development of new antimycobacterial compounds: N-Benzylsalicylthioamides

Abstract

The group of new derivatives of N-benzylsalicylthioamides was synthesized and the compounds were tested for in vitro antimycobacterial activity against Mycobacterium tuberculosis, Mycobacterium kansasii and Mycobacterium avium; Toppliss approach was used for the SAR study