HPLC method development for the evaluation of a novel drug candidate from the group of aroylhydrazone iron chelators (2-pyridylcarboxaldehyde 2-thiophencarboxyl hydrazone-PCTH) in rabbit plasma
Abstract
The aim of this study was to develop and validate HPLC method suitable for the analysis of PCTH in rabbit plasma. Solid-phase extraction was used for isolation of PCTH from plasma.
The developed method was validated (linearity, precision accuracy)