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Transplacental pharmacokinetics of glyburide, rhodamine 123, and BODIPY FL prazosin: Effect of drug efflux transporters and lipid solubility

Publication at Faculty of Pharmacy in Hradec Králové |
2009

Abstract

In this study we investigate the effect of Bcrp and P-gp on the transplacental pharmacokinetics of their specific and common substrates employing the technique of dually perfused rat placenta.