The effect of new proteasome inhibitors, belactosin A and C, on protein metabolism in isolated rat skeletal muscle

Abstract

The aim of our study was to find out the direct effects of new proteasome inhibitors, belactosin A and C (potential anti-tumour agents), on the protein matabolism in isolated rat skeletal muscle. We proved that belactosins affected basic parameters of protein metabolism, the response was muscle- and belactosin-type-dependent.