Charles Explorer logo
🇬🇧

New potential antituberculotics with thioxo group

Publication at Central Library of Charles University, Faculty of Pharmacy in Hradec Králové |
2009

Abstract

The goal of this work was synthesis of new chemical compounds with antimycobacterial activity which can represent new potential antituberculotics. The goal vas to synthetize a series of new N-(4-alkylphenyl)salicylamides, 3-(4-alkylphenyl)-2H-1,3-benzoxazine-2,4(3H)-diones and adequate 3-(4-alkylphenyl)-4-thioxo-2H-1,3-benzoxazine-2(3H)-ones and 3-(4-alkylphenyl)-2H-1,3-benzoxazine-2,4(3H)-dithiones.

Ethyl, sek-butyl and butyl was used as alkyl.