Abstract
The aim of this dissertation thesis was preparation of drug delivery systems for polyene antimycotics, especially amphtotericin B(AmB). Series of pH-sensitive conjugates of AmB with substituated poly(ethylene glycols) (PEG) have been synthesized and characterized for this purpose.
Part of the thesis was dedicated to study of physical-chemical properties of poly(ethylene glycol)-b-poly(amino acid) block copolymers.