Primary ciliary dyskinesia: Part 1. - Pathogenesis and clinical presentation

Abstract

Primary ciliary dyskinesia is a hereditary disease characterized by abnormalities in ciliary structure or function. This review aims to summa-rize recent knowledge about primary ciliary dyskinesia targeting mainly the pathogenesis and clinical symptoms.

PCD is more frequent than previously presumed and a number of patients do not have set correct diagnosis.

Keywords

• Chronic respiratory disease
• Cilia
• Primary ciliary dyskinesia
• Situs viscerum inversus