Association of the pernicious anemia and the gastric carcinoid with the type 1 diabetes mellitus - or autoimmunity with an impaired hormonal regulation in the real practice
Abstract
A 55 years old patient with type 1 diabetes mellitus and proved microangiopatic complications was hospitalized for vertigo and a slowly progressive quadruparesis. Initial laboratory tests suggested the pernicious anemia, which was proved by a diagnosis of atrophic gastritis by gastroendoscopy that also revealed two polypose formations, one of them was formed by the carcinoid.
Clinical symptoms of this neuroendocrine tumor are not frequent, but its incidence has increased in last decades and it is associated with a paracrinne deregulation in a gastric mucosa in atrophic gastritis. Following a successful treatment of the carcinoid the patient needs a further follow-up care due to a risk of a gastric cancer that develops in up to 6 % cases.
The presented case report highlights a careful assessment of symptoms of so called associated autoimmunity, which was the underlying cause of the autoimmune chronic atrophic gastritis inducing not only the pernicious anemia but also the carcinoid.