Abstract
According to the results of the first extensive prospective study called Pregnancy In Multiple Sclerosis (PRIMS), from the year 1998, pregnancy has no negative influence on the development and progression of the disease. The patient should be well stabilised during the year leading up to a planned pregnancy.
Chronic therapy is usually discontinued prior to pregnancy, the precise timing of that depends on many factors, especially the severity of the disease and the type of therapy in use. Patients with multiple sclerosis should be concentrated in specialised risk advisory centres for pregnant women, which cooperate with MS centres.
Care should be taken so that the delivery goes as gently as possible, preferably "per vias naturales".