Involvement of epithelial-mesenchymal transition in urinary bladder cancer progression. A review

Abstract

Epithelial-mesenchymal transition (EMT) is a morphogenetical process involved in embryogenesis and - as evidenced by a growing amount of reports - in the progression and metastasation of at least a subset of human malignant tumours. This review gives a brief description of the current EMT concept and summarizes findings relevant to urinary bladder cancer.