Abstract
Hyperactive bladder is defined mainly by urgency (strong urge to micturize, which is difficult to suppress), with or without incontinence, usually also with frequent urination (frequency, ie micturition more than eight times in 24 hours) and nocturia ( nocturnal urination, which is the cause of sleep interruption). Its prevalence increases with age.
Individualized pharmacotherapy is the method of choice in the treatment of overactive bladder. Therapy is based on anticholinergic drugs, which are highly effective, but their use is often associated with significant side effects (xerostomia, xerophthalmia, accommodation disorders, constipation), which are the main reasons for discontinuation of treatment.
Postmenopausal therapy includes topically vaginally administered estrogens to help reduce the dose of anticholinergics while maintaining an overall high efficacy. Pharmacotherapy of overactive bladder usually does not achieve 100% efficacy, but helps to significantly improve quality of life.