Abstract
It has long been known that in adult patients treated for chronic renal insufficiency, resp. Renal failure are more random complicators of cardiovascular disease.
Pediatricians with poor solutions to complicated patients suffering from late, when the main interest has long been focused on renal osteodystrophy and growth disorders. Recently, however, calcium phosphate metabolism and its relationship to myocardial and vascular damage have been performed in the foreground and in pediatrics; witnesses to a number of recent reports in renowned periodicals.
Recalculating to what is happening in pediatrics, searches for examination methods began to reveal signs of preclinical atherosclerosis and calcium deposits in the myocardium and blood vessels in the early stages of renal insufficiency (CIMT - carotid intima-media thickness) beam computed tomography, FMD - flow - mediated dilatation - sonographic examination of endothelial dysfunction of peripheral arteries). These examinations objectify the earlier stages of atherosclerosis in the period before calcium deposition (AHA classification I-III).
The levels of calcium, phosphorus, parathyroid hormone, the size of the calcium phosphate product and hypertension play a key role in the diagnosis, prevention and treatment of diseases of the cardiovascular system. It should be borne in mind that it is possible to survive for a long time in patients who have been found to be able to be treated by dialysis or transplantation in childhood, to damage the cardiovascular system while they are in the care of pediatricians.
Advances in the management of these complications await their newer phosphate binders without calculation and analogous vitamin D. These help to limit the absorption of calcium in the intestinal tract to successfully suppress secondary hyperparathyroidism.
Another possible consequence is the control of hypertension, which is common in pediatric patients with renal impairment and contributes to the risk of atherosclerotic changes.