Abstract
This article summarizes possibilities of small scale preparation of non-sterile dosage forms with systemic effects designed for pediatric population. Suitability of dosage form depends on route of administration, age of children and physical-chemical and biopharmaceutical properties of drug substance.
If the active pharmaceutical ingredient (API) is not available as a raw material, it is possible, under certain circumstances, to modify the licensed product to suitable form for pediatric administration with required dosage of API. The pharmacist is responsible for quality, stability and content of drug during shelflife.