Abstract
Liver transplantation as an organ is the only causal therapeutic method in the treatment of acute and chronic liver disease failure and in the treatment of inherited metabolic disorders. A suitable organ donor is not always found.
Therefore, it is an effort to look for others alternative methods of increasing the survival of patients with liver disease. One of them is a liver cell transplant.
Advantages of hepatocyte transplantation over liver transplantation as an organ: Liver cell transplantation is a relatively simple procedure, possible to perform on an outpatient basis, the method is less for the patient invasive. During liver cell transmission, we expect a lower immune response of the body, so the amount can be reduced administered immunosuppressants.
Hepatocytes obtained from a single organ can be used for multiple recipients. In addition, liver cells are possible freeze and retain, while retaining their proliferative capacity.
Hepatocyte transplantation can be used to bridging the time until a suitable organ donor is found. Lower economic costs are not negligible.