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Diabetes mellitus and ischemic heart disease

Publication at Second Faculty of Medicine |
2005

Abstract

Mortality in patients with sdiabetes mellitus for ischemic heart disease is high. Diabetes mellitus is itself a risk factor for ischemic heart disease; type 2 diabetes is characterized by the presence of other risk factors (dyslipidemia, procoagulant status, insulin resistance, hypertension, hyperuricemia).

Current intensive and consistent treatment (metformin, glitazones, statins, ACE inhibitors) of patients with diabetic drugs has been shown to reduce morbidity and mortality from cardiovascular complications. Until recently, the prognosis of a patient with diagnosed type 2 diabetes mellitus was critical, surviving an average of 7-8 years from the time of diagnosis.

Epidemiological studies have shown that the most common cause of death is cardiovascular disease, of which ischemic heart disease is the most common (cause of death in 50-60%). After identifying the basic modifiable risk factors for coronary heart disease in the general population, and at the same time providing evidence of the opposing contribution of these risk factors to mortality in secondary and primary prevention, attention was focused on studying risk factors and the importance of influencing them in patients with diabetes. mellitus.

It is worth noting that although diabetes was soon recognized as a risk factor for coronary heart disease, it took a relatively long time for medicine to address the special issues of the relationship between diabetes mellitus and coronary heart disease, and even longer for secondary and primary preventive studies. addressing this issue, especially for people with diabetes. However, the results of the studies are currently a good guide for determining the optimal treatment of a patient with sdiabetes mellitus (especially type 2) in relation to the prevention of cardiovascular events.