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Carcinoma of the Pancreatic Head and Periampular Carcinomas. 10-year Results of their Resection Management

Publication at Second Faculty of Medicine |
2005

Abstract

Introduction: Parcial duodenopancreatectomy (DPE) remains the principal treatment method of carcinomas located in the region of the pancreatic head. Although several surgical clinics use this method, assessment of, mainly the long-term, treatment results is virtually absent in our literature.

Aim: Presentation of early and late results of the procedure collected in a clinic, managing the procedures with „medium frequency“. The study is aimed at patients with histologically confirmed carcinomas of the pancreatic head.

Material and methods: Prospective data from a group of patients who had undergone the DPE during the 10-year study in the Surgical Clinic of the IInd Medical Faculty of the Charles University in Prague-Motol, have been collected. Results: From January 1995 to the end of 2004, 121 DPEs were completed, the 30-day mortality rate was 4.9% and the morbidity rate reached 17.5%.

The long-term results were assessed in 71 cancer patients – the median survival rate was 18 months following the procedure (1–121 months), depending on the tumor type. Conclusions: The collected results are similar to those presented by foreign clinics (but conducted with lower frequencies here) and fall within a European better average.