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Strictures of the terminal bile duct - who profits from the surgery?

Publication at Second Faculty of Medicine |
2005

Abstract

Background : Elucidation of the etiology of terminal bile duct strictures is oftentimes challenging. In choosing the optimal treatment method, a multidisciplinary approach is necessary.

Aims and methods : To demonstrate the advantages and indications of surgical management, 153 patients with terminal bile duct strictures were retrospectively analysed. All patients had been treated during a period of eight years (1(st) January 1995 - 31(st), December 2002) in same department.

The principal datas studied were surgical morbidity, thirty-days' mortality rates and recurrence of jaundice. Results : During a period of eight years, 153 patients (100%) underwent laparotomy.

Radical surgery (duodenopancreatectomy) was performed in 79 patients (51.6%), while 74 others (48.4%) benefited from bypass procedures. Postoperative morbidity reached 13, 1 %; nine patients (5.9%) died within the thirty days of surgery.

Recurrence of jaundice was observed in three patients (1.9%). Conclusion : Surgical management of terminal bile duct strictures is indicated in most patients with benign strictures, strictures of unknown origin and with malignant strictures, where the patients are in a reasonably satisfactory clinical condition.

The surgical approach provides the potential advantage to obtain a definite histological diagnosiscare and to remove the tumour in many patients. Patients with non resectable tumours could benefit from bypass procedures ensuring long-term and effective drainage of the bile.