Abstract
Introduction: It is a well known fact that precise diagnostics of small intestine disorders - bleeding disorders being one of the most serious ones - represents a demanding problem. A new method of using the M2A endoscopic capsule is a diagnostic solution for these disorders.
This paper targets on comparing the results of M2A capsule use and routinely performed push-enteroscopy. The aim of the study: The goal of our observation was to find out the diagnostic importance of the M2A capsule in comparison with push-enteroscopy within a randomized comparative study, and to compare our results with those of other authors.
Material and methods: Our cohort consisted mainly of patients aged 18+ years suffering from GI bleeding disorders, source of which was not explained using commonly used methods (gastroscopy enteroscopy, enteroclysis). These patients underwent examination using the M2A capsule and enteroscopy.
The choice of patients for this examination was based on random choice of even and odd numbers. Results: 250 patients were examined between 2005 and 2007 in our cohort, of which 129 underwent an examination by the M2A capsule and 121 by push-enteroscopy.
The most frequent praeliminary-diagnoses were: unexplained small intestine bleeding, hypochrome anaemia and inflammatory bowel disease. The objectively proved pathological findings showed high percentage of both sensitivity and specificity of the M2A capsule method, especially in unexplained small intestine bleeding.
The positivity rate in malabsorption syndrome was also high. Conclusion: The advantages of the M2A capsule method are: high diagnostic yield, non-invasiveness and patient comfort.
Therefore, the M2A method should be used as a method of choice in GI bleeding disorders.