Increased serum parathyroid hormone concentration with normal serum calcium levels in patients operated for primary hyperparathyroidism
Abstract
The article is concerned with the etiology of a postoperative increase in serum parathyroid hormone (PTH) level in patients successfully operated for primary hyperparathyroidism (HPT) who have normal postoperative calcium levels. Most authors agree on this being secondary HPT due to hypovitaminosis D and hungry bone syndrome [1].
It is contributed to by metabolic changes caused by primary HPT and restricted calcium intake in the preoperative period, resulting in skeletal demineralization. Other works, however, relate secondary HPT in patients operated for primary HPT to the age, adenoma weight and renal functions, bone metabolism markers, bone density and race.
Recurrent and persistent hyperparathyroidism account for approximately 1-2 % of cases and are not dealt with in the article.