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Prognostic value of clinico-pathological factors in patiens with TaT1 bladder carcinoma

Publication at Second Faculty of Medicine |
2011

Abstract

Aim: The aim of our study is to assess significance of different prognostic factors in patients with TaT1 bladder tumour. Methods: There were 178 men and 68 women enrolled in the study, mean age 66.8 years (18-90 years).

Patients were devided into groups according to tumour stage, grade, miltiplicity and concomitant carcinoma in situ (CIS). We focused on evaluation of recurrence and progression free survival.

Results: Tumour T1 was found in 98 (33%) patients, Ta in 119 (48%) patients. Tumour G1 was found in 80 (33%), G2 in 105 (43%) and G3 in 42 (17%) patients.

The tumour was multiple in 107 (43%) cases and solitary in 139 (57%) cases. Concomitant CIS was described in 6 (2%) patients.

As a significant prognostic factor of recurrence free survival was found tumour grade (p = 0.0464) and multiplicity (p = 0.0459). Significant prognostic factor of progression was tumour stage (p = 0.001) and grade (p = 0.001).

Conclusion: We conclude that assessment of clinicopathological prognostic factors in patients with TaTl bladder tumours is useful for stratification of their follow-up and treatment. Our results cordate with other authors.