Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum

Abstrakt

Metallothioneins belong to the group of intracellular, high molecular and cysteine-rich proteins whose content increase with increasing concentration of a heavy metal. Here we applied the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothionein in human blood serum of patient poisoned by lead and/or treated by platinum.

The increased metallothionein concentrations in both cases were observed.

Klíčová slova

• Metallothionein
• Brdicka reaction
• Peak H
• Catalytic hydrogen reaction
• Cancer, Lead
• Differential pulse