The available studies indicate that the etiology of psoriasis may be extremely diverse in individual patients. It is known that its prevalence in the population is affected by genetic, environmental, immunological, viral, infectious, biochemical, endocrine, and psychological (trauma, stress), factors as well as alcohol and drug abuse Psoriasis is associated with cardiovascular abnormalities; moreover, it increases the risk of the numerous diseases, including atherosclerosis, metabolic syndrome, dyslipidemia, hypertension, diabetes type 2, obesity, cancer, depression, osteoporosis, chronic obstructive pulmonary disease,and even cerebral stroke.