Abstract
Radical resection of metastases is currently the most effective treatment modality in patients with liver metastases of colorectal cancer. Conversion therapy is effective for the patients, whose metastases are not primarily resecable.
With this therapy is achieved a downsizing in 25%, followed by performing liver resection. Large hepatic resection and biochemotherapy is suitable to perform at the specialized department on which is guaranteed a multidisciplinary approach to treatment.
This approach not only guarantees low operating risk and use adequate (neo)adjuvant therapy, but also the complexity of reaching more than 50 % five year survival with good quality of life. Further improvements in the lives of patients is subject to an early transition to an individualized approach and personalized approach to treatment.