Publication at First Faculty of Medicine, Faculty of Physical Education and Sport, Second Faculty of Medicine |
2006
Abstract
Brain trauma typically leads to neuronal damage and loss. Assuming a transient autoimmune response to debris of the damaged neurones, we have monitored serum titres of IgG and IgM antibodies to beta-tubulin class III (beta TcIII), which is almost exclusively found in neuronal cytoskeletons.
In 15 out of 18 patients, the peak of the IgG or IgM antibody titre appeared in the serum within 3 weeks of a brain trauma.