Abstract
Acute lymphoblastic leukemia (ALL) is one other childhood cancer. Approximately 65 children suffer from it annually in the Czech Republic.
The History of Pediatric ALL Treatment is the history of one of the best therapeutic successes in hematology and oncology ever. Even at the beginning of the 1960s, the curability of children's ALL was practically zero.
At the turn of the 20th and 21st centuries, a child who suffers from this disease and is treatable according to a modern treatment protocol already has a chance of a complete 75% cure. However, the name VŠE obscures the fact that it is not really a single homogeneous disease, but rather a summary of precisely precisely immunophenotypes and genotype-characterized subgroups.
These subgroups differ in typical age at onset, response to treatment, and, of course, prognosis.