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Spatial navigation as a cognitive domain in the diagnosis of mild cognitive impairment

Publication at Second Faculty of Medicine |
2011

Abstract

Alzheimer's disease is from its start associated with a spatial disorientation. In most cases it's preceded with the mild cogni tive impairment, which subtypes of different expected outcomes of the disease are distinguished by psychology tests focused on memory and other cognitive do- mains.

Using a simple navigation test in a real space and on a computer monitor we compared the deficits in patients with mild cognitive im- pairment in standard cognitive tests and in spatial navigation. The navigation test was performed in a spatial cognition labora tory, called Blue Velvet Arena, placed in Teaching Hospital Motol.

The simple navigation task evaluates three modes of spatial navigation: cued, using proximal orientation cue, allocentric, using distal orientation cue, and egocentric, using current subject position. Our preliminary res ults suggest that standard cognitive test did not predict the results in spatial navigation tests and spatial navigation can therefore represent an independent co- gnitive domain.