Ischemic mitral regurgitation (MR) is a state of functional insuffi ciency of the mitral valve due to coronary artery disease. Myocardial infarction with papillary muscle rupture is the cause of acute MR.
Immediate surgery is the only effective treatment, however it is associated with very high risk. Left ventricular abnormalities with structurally normal valve and papillary apparatus are the cause of chronic MR.
Significant regurgitation, defi ned by the effective regurgitant orifi ce >= 20 mm2, is indicated for correction at the time of revacularization surgery, the indication for surgical MR treatment without revascularization, or in mild MR at the time of revascularization is a matter of ongoing discussion.