Isoenzymes of alkaline phosphatase in a child after bone marrow transplantation with detached graft versus host disease

Abstract

We describe the case of a 13-month-old child with highly increased ALP in serum (S-ALP 24.7 μkat/l) after bone marrow transplantation and subsequent liver graft versus host disease. We performed laboratory investigation of isoenzymes of alkaline phosphatase and we detected unusual fraction.

We suggest that it corresponds of a complex of ALP with lipoprotein X.

Keywords

• alkaline phosphatase
• isoenzymes of ALP
• lipoprotein X.