Abstract
PAES II is an autoimmune disorder of two or more endocrinal glands often associated with an autoimmune disorder of non-endocrine organs. The case history presents a female patient with the autoimmune thyreopathy who presented in a connection with an increase of thyroid gland substitution by levothyroxine with so far undiagnosed hypocorticalism caused by the autoimmune adrenallitis.
Concurrently, the premature menopauses caused by the autoimmune oophoritis was present, in addition to that, during the screening on organ specific antibodies a presence of ICA antibodies was detected, which may indicate presence of an asymptomatic prediabetic stage.