Are we justified to classify patients with two unrelated clones with del(5q) and trisomy 8 as a subgroup of myelodysplastic syndrome of the type of 5q-syndrome?

Abstract

Among the 106 patients with myelodysplastic syndrome (MDS) of the type 5q minus syndrome, we found 11 patients who comply with the criteria od this syndrome. In addition to the del(5q) clone they were found to have the unrelated, independent trisomy 8 clone.

All these patients were female.

Keywords

• 5q-syndrome
• biclonality
• del(5q)-trisomy 8